So the cancer came back again. My “break” which was
filled with pericarditis and hernia surgery turned out to not be such a break,
and now while I was recovering from both of those, I had my second recurrence. I
was immediately put back on full chemo- Ironotecan with Cyramza for three
months. My schedule of treatment was three weeks on and then one week off. It sucked!
What sucked even more was that it wasn’t working. My CEA was steadily climbing;
at the end of May 2017 it was 8.2, and by August 16th it had risen
to 46.9. My number hadn’t been that high since June 2014! With the CEA trending
upward it was clear that my cancer had grown resistant to the Cyramza, so my
oncologist changed my cocktail to include Vectibix in place of Cyramza. Good
news/bad news about the Cyramza being gone. Good news: no more excessive
flatulence! I enjoyed that going away as I was never one of the “pull my
finger” crowd, and the amount I was farting went from embarrassing to comical
and back a few times over. Bad news: that drug, and the others in that family are
no longer viable treatment options for me anymore. This is scary because there
are a limited number of treatment options out there and this one was just
scratched off the list for me. In addition, there is no guarantee that the other
available drugs will work. Eventually the cancer will grow resistant to all the
treatments, and I’ll die. But as Arya Stark would say, “Not today!”
Starting
a new treatment is always nerve wracking (as if having Stage IV colon cancer
wasn’t nerve wracking enough) because you never know if the new treatment will
work. So we started with Ironotecan and Vectibix. Good news/bad news about
Vectibix. Good news, after the first treatment the number dropped from 46.9 to
21.5. It was working! (insert Snoopy ‘Happy Dance” here) Better news: it
continued to work and the number continued to drop to the lowest levels I’ve
ever had on a consistent basis, <.5. Bad news: when Vectibix is working you
get a nasty, itchy pimply rash. I had acne in high school, but it wasn’t nearly
as bad as this. It covered my face, neck, scalp and torso fully, and went
lightly down my arms and legs. The oncologist gave me Doxycycline, which helps
with the rash not getting infected, and Prednisone, which helps the itching-
most of it anyway. Sun, heat, and sweating all aggravate the rash and itching,
and it’s hard to avoid heat here in south Florida- thank G-d for air
conditioning! The rash is uncomfortable and ugly. A side effect of a side
effect is the 15 pounds I’ve gained from the Prednisone. One odd side effect is
super eyelash growth. My eyelashes grew so much that I had to ask my wife to
trim them multiple times because they scrape against my eyeglasses and smudge
them. The lashes on the outside were so long, they were touching my eyebrows.
Yet another odd request for a spouse/partner brought to you by the cancer/chemo
experience, ”Um, sweetie, would you mind trimming my eyelashes for me?” I’ve
always had long eyelashes; I’ve been lucky in that- now they’re crazy!
In
addition to crazy eyelashes, my nose hair grew coarse and out of control, but
luckily my beard trimmer has a nose hair trimmer attachment. While I have the
rash on my face, neck and torso, the skin on my fingertips have become dry and they
would split open without warning. Imagine getting paper cuts without touching
any paper. The skin on my fingertips has changed so much the fingerprint ID on
my phone doesn’t recognize my thumb.
After
four months of the new treatment, and shrinking numbers I had a PET scan. The
CEA by that time was well below the NED (No Evidence of Disease) threshold. In
the past when my number was down that low I was NED- even if only temporarily.
Not this time. The PET showed there was still one lymph node behind my stomach
that was enlarged, but not active. It was dormant. My oncologist said he
doesn’t like dormant, he likes eradicated. The analogy he used was that there
was a bear in a cave and it was sleeping. It will eventually wake up. I
replied, “Let’s go kill the bear.” I would have three more months of treatment
and then another scan. March 2018, was time for that scan- this time a CAT
scan. Good news: the lesion shrunk even more- from 1.9 cm to 1.6 cm. Bad news:
to be considered NED (and to have killed this bear) the lymph node had to be
1.5 cm or under. The oncologist was happy- “It’s still shrinking,” and then
ordered two more months of treatment. We’ll have to wait and see what the scan shows
after that…
